The CRP Rapid Test Device (Whole Blood/Serum/Plasma) is used for semi-quantitative determination and monitoring of CRP concentrations in whole blood/serum/plasma specimens.

C-reactive Protein (CRP) in patient`s sera has been found in association with acute infections, necrotic conditions and a variety of inflammatory disorders.
There is a strong correlation between serum levels of CRP and the onset of the inflammatory process. Monitoring the levels of CRP in patient`s sera indicates the effectiveness of treatment and the assessment of patient recovery. It is used in particular to differentiate bacterial infections from virus infections.

The CRP Test Strip is an immunochromatographic test, based on two specific antibodies against human CRP. The concentration-dependent formation of test lines allows a rapid semiquantitative determination of CRP in whole blood
samples.
The tip of the test strip is dipped into the test sample which is diluted with buffer solution. The sample now moves through the test strip from bottom to top. If the test sample contains CRP, it attaches to the first anti-CRP antibody which is conjugated with a red gold colloidal for color marking. The red CRP antibody-gold complex, together with the sample liquid, diffuses through the membrane that is pre dispensed with lines of different
amounts of the second anti-CRP antibody. The CRP-antibody-gold complex is immobilized by the antibodies coated on the membrane leading to the formation of red lines. The number of lines depends on the CRP concentration in the sample.
The more CRP is contained in the sample, the more red lines become visible.
The control line serves as a procedural control and indicates that sufficient volume of specimen has been added and membrane wicking has occurred.

SUPPLIER:SPAN BIOTECH LTD.

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