HPMC is actually a methyl cellulose modified by epoxy methane (methyl oxypropyl ring), so it has similar characteristics of methyl cellulose soluble in cold water, insoluble in hot water, solubility in organic solvents is better than water soluble, it can dissolve in anhydrous methanol and ethanol, It can also be dissolved in chlorinated hydrocarbons such as dichloromethane, trichloroethane and organic solvents such as acetone, isopropyl alcohol and diacetone alcohol.